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IJAMMR.,   Volume(2) - Issue(2), 2017
pp 12-23,   https://dx.doi.org/10.18831/djmicro.org/2017021002

Individual and Combined Antibacterial Activity of Honey and Medicinal Herbs against some common Clinical Pathogens

C R Shalinimol;C Asha Priya


In this present investigation, the individual and combined action of honey and five herbal extracts like ginger (Zingiber officinale), garlic (Allium sativum), liquorice (Glycyrrhiza glabra), purple fruited pea eggplant (Solanum trilobatum) and Indian Acalypha (Acalypha indica) were tested against five common clinical pathogenic bacteria such as Bacillus sp., Klesiella sp., Psudomonas sp., Streptococcus sp. and Staphylococcus aureus. All the bacterial isolates were less susceptible to honey and the plants individually. But both honey and the herbs combined together and played a good role against the pathogens. Garlic with honey acted more against S. aureus (22mm), Bacillus sp. (20mm), Klebsiella sp. (16mm) and Streptococcus sp. (12mm). Ginger with honey was highly active against Pseudomonas sp. (18mm) and Streptococcus sp. (14mm). Liquorice with honey was active against Pseudomonas (19mm) and Streptococcus sp. (13mm) and purple fruited pea eggplant with honey was highly effective against Streptococcus sp. (17mm). Acalypha did not play a good role against these pathogens but Streptococcus with 9mm and Klebsiella with 8mm zone could produce a suitable action. All the tested bacteria were sensitive to a mixture of honey and garlic and all the plants with honey could inhibit the growth of Streptococcus sp. In the case of minimal inhibitory concentration, 1.8 to 2ml of the mixture of the plant extracts and honey made a complete destruction of the pathogens. All such outcomes in total, exhibit the possible applications of these medicinal herbs combined with honey against many bacterial diseases.


Honey, Zingiber officinale, Allium sativum, Glycyrrhiza glabra, Solanum trilobatum, Acalypha indica.

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